VEGA lives because it is based on sponsors, supporters, developers and evaluators.

The developers are involved in the continuous improvement of the platform, also on the basis of the feed-back and comments from the evaluators, which use and check the platform.



Istituto di Ricerche Farmacologiche Mario Negri IRCCS.

The Laboratory of Environmental Toxicology and Chemistry, headed by Dr Emilio Benfenati, has coordinated 15 EC funded projects and participated to other 18, many of them on QSAR.

Istituto Mario Negri is the coordinator of the VEGA project.


Politecnico di Milano

Department of Electronics and Information

The group headed by Prof Giuseppina Gini has coordinated the EC funded projects EST on hybrid systems for QSAR. It has also participated to many EC funded projects, developing and using QSAR models.

Politecnico di Milano provided a model for mutagenicity and the SARpy software.


The Food and Environment Research Agency (Fera)

Fera is an Executive Agency of the UK’s Department for Environment, Food and Rural Affairs (Defra), and has over 900 highly qualified staff and state-of-the-art R&D facilities. Fera scientists are also active members of various UK and EU committees, and are influential in providing scientific input to support policy and regulatory decisions. The QSAR team at Fera, headed by Dr. Qasim Chaudhry, has participated in a number of projects on assessment of data quality, and development and application of regulatory QSAR models.

FERA contributed to the development of the CAESAR models.

QSAR-related Projects



For more than 15 years KnowledgeMiner Software creates knowledge mining tools that enable anyone to use data modeling to quickly visualize new possibilities. It has been doing research and consulting in several fields. One of these fields it has been active in more intensely is about modeling and prediction of toxicological and ecotoxicological hazards and risks of chemical compounds also for regulatory purposes with the goal to substitute and minimize still widely used animal tests by computer models.

KnowledgeMiner provided the tool for the sensitivity evaluation included in the Applicability Domain.

QSAR-related Projects

Kemijski inštitut

Kemijski inštitut

Laboratory of Chemometrics

National Institute of Chemistry (NIC). The Laboratory of Chemometrics, headed by Dr Marjana Novič, has coordinated one and participated in several EC funded projects on QSARs.

Marjana Novič has participated in many EC funded projects that included cheminformatics for data analysis.

Kemijski inštitut provided the model for carcinogenicitiy.

QSAR-related Projects



Kode is a young scientific consultancy company working in the field of data science, composed of experts in several fields: multivariate statistics, data mining, chemometrics and chemoinformatics. Besides providing consultancy services to companies and authorities, they focus on the design and development of innovative software tools for QSARs and other chemoinformatic applications. They have been part of the development team of the VEGA stand-alone application.

Kode is the main responsible for the implementation of the models within VEGA and the main developer of stand alone version.


US Environmental Protection Agency

National Risk Management Research Laboratory

The group headed by Douglas Young and Todd Martin have developed a variety of QSAR techniques (including hierarchical clustering and group contribution based methods) to estimate toxicity values from molecular structure. They have developed T.E.S.T. (Toxicity Estimation Software Tool) which allows users to easily enter chemical structures and then estimate toxicity values, molecular descriptors, and physical properties.

US EPA provided model for developmental toxicity and databases of substances with known structures and experimental values for several endpoints.