VERMEER FCM
VERMEER Solvents
April 10, 2022
Within the LIFE VERMEER project, a new software system to support the risk assessment of chemicals intended to be used in plastic Food Contact Materials (FCM).

Within the LIFE VERMEER project, a new software system to support the risk assessment of chemicals intended to be used in plastic Food Contact Materials (FCM) has been developed. The software allows to model the migration of chemicals from FCM into food and to predict several toxicological endpoints relevant for FCM compounds.

The software, freely available, has been designed in line with the regulatory framework for plastics FCM (Regulation EU No 10/2011)

Toxicological data requirements for plastic FCM compounds are driven by the migration of the compound into the food. VERMEER FCM allows to predict the concentration of chemical migrants in food in contact with plastic FCM providing at the same time predictions for a series of toxicological endpoints. The user is asked to provide the information regarding the chemical(s) of interest, the FCM and the food concerned, and other important parameters such as the contact time between food and FCM, contact temperature and some physico-chemical properties of the chemical migrants in order to launch the simulation.

The software allows to run both deterministic and probabilistic simulations.

Features

  • Freely available: no registration required.
  • One-shop system: one-shop system for the risk assessment of plastic FCM.
  • High covering: hazard and exposure (i.e. migration) assessment within one platform.
  • Migration model included: migration model available to estimate the concentration of migrating chemicals in food.
  • QSAR models inside: models for mutagenicity, chromosome damage, No Observed Adverse Effect level (NOAEL), carcinogenicity and developmental toxicity included.
  • Detailed output: deterministic and probabilistic simulation possible.
 
 

VERMEER FCM v3.4 is included in the latest version of MERLIN-Expo (version 4.0.29)

To download the installer, setup_MERLIN-Expo_4.0.29_XXbit.exe, visit the MERLIN-Expo official site

If you have a previous version installed, you can update it by starting MERLIN-Expo and accepting the download of the updates in the Update notification that is prompted.
To run the VERMEERFCM v3.4 tool: Go to ‘New’ and in the ‘Open template’ window select VERMEERFCM v3.4 Note that the user manual is not included in the model. Instead, the description of the tool (‘Information tab’ – ‘Description’) includes the link to access the manual

 

Developed by

  • logo AF Facilia
  • logo angel consulting
  • logo bfr
  • logo EDF - Electricité de France SA
  • Ineris logo
  • Istituto di Ricerche Farmacologiche Mario Negri - IRCCS
  • KODE chemo informatics logo