A new read-across tool, called VERA, for carcinogenicity and fish acute toxicity is available.
VERA Virtual-Extensive-Read-Across is a new open-access software for chemical read-across.
Within the EC-funded LIFE project CONCERT REACH, the new open-access software for chemical read-across VERA has been developed. Read-across applies the principle of similarity to identify the most similar substances to represent a given target substance in data-poor situations. However, differences between the target and the source substances exist. VERA (Virtual Extensive Read-Across) provides a means to assess the similarity between chemicals using structural alerts specific to the property, pre-defined molecular groups and structural similarity. The software finds the most similar compounds with a certain feature e.g. structural alerts and molecular groups and provides clusters of similar substances while comparing these similar substances within different clusters.